منابع مشابه
Antiviral drugs for cytomegalovirus diseases.
Cytomegalovirus infections are associated with severe morbidity and mortality is patients at risk for disease because of immune system disabilities; in particular, recipients of stem cell (HSCT) or solid organ (SOT) transplants. There are three systemic drugs approved for CMV treatment: ganciclovir, or its prodrug valganciclovir, foscarnet, and cidofovir. An anti-sense therapeutic, ISIS 2922, i...
متن کاملA survey of antiviral drugs for bioweapons.
Smallpox (variola major), and the haemorrhagic fever viruses (filoviruses and arenaviruses) are classified as Category A biowarfare agents by the Centers for Disease Control. Category A agents pose a significant risk to public health and national security because they can be easily disseminated by aerosol, although with the exception of variola, they are not easily transmitted from person to pe...
متن کاملTug of war for antiviral drugs data.
Tom Jefferson can recite the details of every published study on the neuraminidase inhibitors oseltamivir (Tamiflu) and zanamivir (Relenza): date of publication, authors’ names, journal title, research question, methods, funder, and findings. But what has occupied the mind of the physician-academic from Cochrane’s Acute Respiratory Infections Group for the better part of five years is another d...
متن کاملPreclinical development of antiviral drugs.
The early preclinical development of an antiviral agent is accomplished essentially in two stages. The first stage consists of gathering data to estimate the potential therapeutic index of the agent. This process includes testing for antiviral activity and for cytotoxicity in vitro and performing preliminary pharmacokinetic and toxicology studies in vivo. The second stage consists of carrying o...
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We thank all the respondents to the survey and the nurses at the Leicestershire Hospice for their interest and willing participation, Dr Carol Jagger for statistical help, and Miss K Jeffery for preparing the typescript. I St Christopher"s Hospice Iniformation Service. 1988 Direcion, of liospiCe serz.ices. Svdcnliaini: St (hristopher's Hospice, 1988. 2 Hill F, Oliver C. Hospice-thc cost of in-p...
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ژورنال
عنوان ژورنال: Cancers
سال: 2018
ISSN: 2072-6694
DOI: 10.3390/cancers10060197